Cureus presents an equitable, efficient publishing and peer reviewing expertise with no sacrificing publication periods. When you skip a dose of this medicine, skip the skipped dose and return to your regular dosing agenda. Never double doses. Methadone medication is especially personalized fo

Renal impairment: The kidney is the most important route of elimination, so pharmacokinetics is altered in sufferers with renal impairment. For that reason, clinicians should really prescribe codeine at a minimized dose or with extended dosing intervals. If you cease taking the medicine